Friday 18th Feb 2022
Dr. P. K. PATANJALI
Advisor and expert in various government committees
Topic – Microencapsulation: A promising approach for controlled & targeted pesticide delivery
Pesticides are the promising tools for the sustainable control of economically relevant agricultural pests, but their indiscriminate use results in persistent residues and toxicity towards non-target organisms. These detrimental effects are not limited to toxicity and residue; still, photo-degradation, microbial degradation, and chemical degradation make it lost from the application site, lowering the effectiveness and increasing applications. In recent years, the environmental agency, the scientific community, and regulatory bodies have focused on minimizing hazards concerning health and the environment caused by pesticides, which can be achieved by reducing the dose of chemical pesticides. These have led to a demand for progress in pesticide formulations with maximal efficacy and minimal harmful effects along with dose minimization.
Among the varied pesticide formulation technologies, the microencapsulation of pesticides stands out for multiple benefits, including the enhanced chemical and thermal stability of pesticide delayed release of the active ingredient, which prolongs effectiveness, resulting in fewer timed applications. Other benefits include reduced volatility, degradation,and greater effectiveness. Microencapsulation is a rapidly expanding technology not limited to agrochemicals but also to the food, pharma, and cosmetics industries. It means applying a relatively thin coating of polymers to the active ingredient as a process. In-situ Polymerization, Coacervation, Solvent evaporation, Interfacial polymerization, Ionic Gelation, etc., are the popular methods of achieving microencapsulation of pesticides; among these methods, interfacial polymerization is the most common technique for microencapsulation.
Dr.Purnima Amin
Professor
Department of Pharmaceutical Sciences and Technology, ICT
Topic – Nano Encapsulation and its application in various fields
Nanoscience involves handling of materials, systems and devices at atomic, molecular and macromolecular level. Considering the same, nanotechnology has been positively impacted the field of pharmaceutical science by increasing the shelf-life of products. Nanoencapsulation among which, is technology used in the pharmaceutical, nutraceutical/food and cosmetic industries for enclosing one or more active ingredient. Nanoencapsulation is a method where one or more ingredients are immobilized in some form of matrix or wall at nanoscale. The ingredient is immobilized in the matrix, which is usually called the core or active part of the material, and the outside of the capsule is called the shell, wall ,encapsulant, or carrier material. Protection offered by shell can be permanent or temporal, in which case the core is generally released by diffusion or in response to a trigger, such as shear, pH, or enzyme action, thus enabling their controlled and timed delivery to a targeted site. Nanocapsules are composed of nontoxic polymeric material with an inner liquid core and offer advantages of stability, accurate targeting, and controlled sustained release with reduced side effects. Examples of nanocapsules include biodegradable nanoparticles, dendrimers, polymeric micelles, liposomes, microcapsules, solid lipid nanoparticles, and solid core-shell nanoparticles,etc.Whearas,synthesis methods are chosen depending upon the chemical structure of therapeutic agent, type of application and time of retention inside the body .
Nanoencapsulation has been employed in various delivery systems such as Oral, Parenteral Nasal, Ocular, Otic,Transdermal, etc.It has been known to have peculiar applications such as Protein, DNA and RNA stabilization, Small molecule delivery, Extending circulatory half-life, Modifying drug transport, Clear liquid formulations, Stable colloid dispersions, Controlled release, Targeted delivery, Triggered release,etc.Thus these potential applications of nanocapsulation makes it promising technology for pharmaceutical as well as other fields.
Vineet Mital
Director
Innoleague Technologies Pvt Ltd
Topic : Microencapsulation and its application in Consumer Goods & Coatings
Micro encapsulation is sometimes misunderstood to be simple layering and also sometimes a product range. In the talk some definitions and depth to what can be called micro encapsulation and what should remain a layering exercise is detailed. Micro encapsulation is a technique useful for adding functionality to active by manipulating the release mechanism. Slow or controlled release or in fact no release can be mechanisms and can add value to the concepts
The talk will focus on examples from consumer goods like fragrance, sunscreens, natural and herbal ingredients and also on application in coatings in the areas of self healing, corrosion protection and phase change materials.
Dr. Jyoti Tripathi
Scientific Officer
Bhabha Atomic Research Centre, Mumbai
Topic: Flavour encapsulation for extended stability of essential oils
Abstract
Flavor and aroma compounds are the most important food characteristics affected by processing conditions. Characteristic aroma of a food product is contributed by essential oil present in the product. These essential oils find wide applications in various industries such as food processing, cosmetics and pharmaceuticals. Essential oil which is a combination of aroma compounds of different classes (terpenes, sesquiterpenes, oxygenated compounds) are prone to degradation reactions and losses during handling and storage. The enhanced retention and controlled release of flavor is at highest priority during food processing. Encapsulation is the most successful way not only to preserve but also to enhance the thermal and oxidative stability of essential oils, overcome the limitations of high volatility and make them easier to handle and incorporate in different food systems. Micro- and nano-encapsulation with various emerging techniques are the most suitable approaches to protect these sensitive essential oils and facilitate their industrial applications. Although microencapsulation employing spray drying is the most widely employed technique for flavor encapsulation, nano-encapsulation approaches provide greater loading capacity and encapsulation efficiency, enhanced stability and better control on flavor release profile. The wall materials generally employed are natural or modified polysaccharides, gums, proteins, lipids and synthetic polymers. The selection of wall material relies on the nature of core material, encapsulation process and the intended use of the product. Combination of wall materials e.g. polysaccharide with protein, or polysaccharide with lipid can further improve the encapsulation efficiency and capsule functionality. However, the release behavior of these encapsulates in food matrices and gastrointestinal systems needs to be explored to enhance their application efficiency. Further, food applications of encapsulated flavors could appeal broader consumer market.
Dr. Rahul Nabar
Consultant
Topic: “An Overview of Micro-encapsulation for Fragrance & Animal Feed Applications”
Abstract:
Microencapsulation is finding increasing applications in the domains of Fragrance and Animal Feed Additives. This talk will provide an overview of current industrial practice and emerging trends with a mix of technical and business perspectives. The goal is to provide practitioners a taste of the opportunities that exist for commercializing microencapsulation and also highlight some challenges in this area.
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